Negative 18 F-FDG and Positive 68 Ga-FAPI-04 Findings in a Patient With Acute Exacerbation of Chronic Cholecystitis.
case_report · Level V
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- Record sourced from PubMed, PMID 39397320.
- Also identified by DOI 10.1097/RLU.0000000000005504.
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Abstract
Acute cholecystitis typically exhibits intense FDG uptake of the gallbladder wall. Radiolabeled fibroblast activation protein inhibitor (FAPI) is considered as a potential alternative agent for tumor-specific imaging. We report 18 F-FDG and 68 Ga-FAPI-04 PET/MR findings in a 44-year-old woman with acute exacerbation of chronic cholecystitis. The lesions show negative 18 F-FDG uptake but intense 68 Ga-FAPI-04 uptake in PET/MR. This case highlights the imperative for nuclear medicine clinicians to exercise vigilance when evaluating gallbladder lesions exhibiting intense 68 Ga-FAPI-04 but negative 18 F-FDG uptake.
Medical subject headings
- Fluorodeoxyglucose F18
- Cholecystitis
- Membrane Proteins