SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease.

Hawrylycz, Michael; Kaplan, Eitan S; Travaglini, Kyle J; Gabitto, Mariano I; Miller, Jeremy A; Ng, Lydia; Close, Jennie L; Hodge, Rebecca D et al. · Nat Aging · 2024

basic_science · Level V

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Abstract

The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) is a multifaceted open data resource designed to identify cellular and molecular pathologies that underlie Alzheimer’s disease. Integrating neuropathology, single cell and spatial genomics, and longitudinal clinical metadata, SEA-AD is a unique resource for studying the pathogenesis of Alzheimer’s and related dementias.