Tumor Hypoxia: Long Ignored but Now Detectable and Potentially Actionable.

Mason, Ralph P · Clin Cancer Res · 2024

prospective_cohort · Level II

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Abstract

Oxygen-enhanced MRI was successfully applied to 24 patients with human papillomavirus-associated oropharyngeal cancer. This prospective trial rigorously evaluated reproducibility and changes with respect to tumor radiation. Analyses compared hypoxic volumes and hypoxic fractions. It represents important progress in developing a practical approach to assessing tumor hypoxia in patients noninvasively. See related article by Dubec et al., p. 5620.

Medical subject headings