Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Female Patients and the Elderly: An Update Analysis from the Global Burden of Disease Study 2021.

Danpanichkul, Pojsakorn; Duangsonk, Kwanjit; Ho, Agnes H Y; Laoveeravat, Passisd; Vuthithammee, Chawinthorn; Dejvajara, Disatorn; Prasitsumrit, Vitchapong; Auttapracha, Thanida et al. · Am J Gastroenterol · 2025

cross_sectional · Level IV

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Abstract

To update the global burden of inflammatory bowel disease (IBD) using data from the Global Burden of Disease 2021. Data from Global Burden of Disease 2021 were analyzed to assess the IBD burden. In 2021, there were 375,140 new cases and 3.83 million total cases of IBD. Elderly onset IBD accounted for 11% of incidences. 167 countries increased IBD incidence rate, with rates rising in female patients (APC: +0.06%) and the elderly (APC: +0.14%) but stable in male patients and the overall population. Although the global burden of IBD has decreased overall, it has increased in female patients and the elderly.

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