Systems Vaccinology: Navigating the Future of Personalized Immunity and Next-Generation Vaccines.

Dib, Serena Maria; Wimalasena, Sonia; Graciaa, Daniel S; Rouphael, Nadine · J Infect Dis · 2024

review · Level V

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Abstract

Systems vaccinology integrates a range of "omics" technologies to identify key immune signatures and enhance vaccine development. This approach aids in understanding variations in immune responses, driven by genetics, health status, and the microbiome. Consequently, systems vaccinology helps pave the way for personalized vaccination strategies, essential for addressing diverse populations.

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