Bizarre Parosteal Osteochondromatous Proliferation With Malignant Transformation and Metastases.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 39436029.
- Also identified by DOI 10.3928/01477447-20241016-01.
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Abstract
A patient with a benign bizarre parosteal osteochondromatous proliferation (BPOP) located in the anterior knee was treated with resection in preparation for total knee arthroplasty (TKA). The BPOP reoccurred and was treated with re-resection at the time of TKA. The BPOP reoccurred a second time and underwent malignant transformation to a fungating high-grade pleomorphic sarcoma with metastatic lesions. This case highlights the rare potential of a previously benign BPOP to undergo malignant transformation after recurrence. A wide margin resection may be considered primarily when surgery is indicated to prevent recurrence and its potential sequelae. [<i>Orthopedics</i>. 2024;47(6):e322-e326.].
Medical subject headings
- Bone Neoplasms
- Cell Transformation, Neoplastic
Anatomy
- knee