DIAGNOSTIC AND THERAPEUTIC CHALLENGES.

Rohowetz, Landon J; Davis, Janet L; Lin, Siying; Webster, Andrew R; Mahroo, Omar A · Retina · 2024

case_report · Level V

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Abstract

A 61-year-old woman had worsening vision for 12 years associated with progressive patchy macular chorioretinal atrophy. There was latent tuberculosis and angioid streaks. Testing revealed a pathogenic variant of PRPH2 and a heterozygous ABCC6 variant. Her complex presentation was attributed to PRPH2, which can produce autosomal dominant retinal degeneration.