The role of polymers in enabling RNAi-based technology for sustainable pest management.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39443470.
- Also identified by DOI 10.1038/s41467-024-53468-y and PMC identifier 11499660.
- Licence recorded as CC BY-NC-ND.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The growing global food demand, coupled with the limitations of traditional pest control methods, has driven the search for innovative and sustainable solutions in agricultural pest management. In this review, we highlight polymeric nanocarriers for their potential to deliver double-stranded RNA (dsRNA) and control pests through the gene-silencing mechanism of RNA interference (RNAi). Polymer-dsRNA systems have shown promise in protecting dsRNA, facilitating cellular uptake, and ensuring precise release. Despite these advances, challenges such as scalability, cost-efficiency, regulatory approval, and public acceptance persist, necessitating further research to overcome these obstacles and fully unlock the potential of RNAi in sustainable agriculture.
Medical subject headings
- RNA Interference
- Polymers
- RNA, Double-Stranded