Spinal Neurocutaneous Melanosis.

Demartini, Zeferino; Maeda, Adriano Keijiro; Cardoso-Demartini, Adriane · World Neurosurg · 2025

case_report · Level V

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Abstract

Neurocutaneous melanosis is characterized by melanin-producing cells within the skin, leptomeninges, or brain parenchyma. It is a severe manifestation of congenital melanocytic nevus syndrome and can develop malignant melanomas. The disorder is commonly present in pediatric patients within the first two years of life and has a poor prognosis. We report a case of an 8-year-old male with epilepsy and cognitive deficit presenting spinal neurocutaneous melanosis.

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