A Rare Case of Tumor-Induced Osteomalacia Due to Mesenchymal Tumor at Foramen Magnum Diagnosed Preoperatively on 68 Ga DOTATATE PET/CT.
case_report · Level V
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- Record sourced from PubMed, PMID 39479992.
- Also identified by DOI 10.1097/RLU.0000000000005549.
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Abstract
A 42-year-old man, a known case of FGF23-dependent hypophosphatemia, underwent 68 Ga- DOTATATE PET-CT, which showed a somatostatin receptor-expressing lesion in the left arch of foramen magnum that was correlated on MRI as a soft tissue lesion measuring 2.2 × 1.3 cm. It was excised and histopathologically confirmed as phosphaturic mesenchymal tumor. Postoperatively, patient improved clinically and recovered from hypophosphatemia completely. A distinct focal uptake in a 68 Ga- DOTATATE PET-CT in a patient with tumor-induced osteomalacia needs extensive workup and high degree of suspicion to rule out mesenchymal tumor at nonconventional location as seen in the present case.
Medical subject headings
- Osteomalacia
- Positron Emission Tomography Computed Tomography
- Organometallic Compounds
- Fibroblast Growth Factor-23
- Foramen Magnum