Detection of Small Brain Metastases by 18 F-Thretide PET/CT in Clear Cell Renal Cell Carcinoma.

Cheng, Xin; Hou, Guozhu; Zheng, Rong; Zhang, Jingjing; Wang, Xuejuan · Clin Nucl Med · 2025

case_report · Level V

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Abstract

A 46-year-old woman with a history of radical nephrectomy for clear cell renal cell carcinoma underwent 18 F-FDG and 18 F-Thretid (also known as Al 18 F-PSMA-BCH) PET/CT. Although the 18 F-FDG PET/CT failed to detect any brain metastases, the 18 F-Thretide PET/CT revealed 2 small metastases: one measuring 1.0 × 0.7 cm in the right cerebellum and the other measuring 0.4 cm in the right frontal lobe. These metastatic lesions were subsequently confirmed by brain MRI.

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