Commentary on Gregory et al.: Fear of precipitated opioid withdrawal should not prevent buprenorphine initiation.

Springer, Sandra A · Addiction · 2025

editorial · Level V

Where this comes from

Abstract

Provision of buprenorphine treatment for opioid use disorder is often stymied by clinicians’ concerns for precipitated opioid withdrawal. Gregory et al’s systematic review identified a low level of precipitated withdrawal with buprenorphine induction even among persons who reported fentanyl use. Evidence, not fear should guide treatment.