Cancer-Specific Integrin Imaging With 68 Ga-Trivehexin : A Potential Imaging for Accurate Staging of Thyroid Malignancy.

Singhal, Tejasvini; Agrawal, Kanhaiyalal; Mandal, Srijani; Parida, Girish Kumar · Clin Nucl Med · 2025

case_report · Level V

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Abstract

68 Ga-Trivehexin is a novel radiotracer binding to "cancer-specific integrin αvβ6." 68 Ga-Trivehexin has high specificity for tumor cells and, thus, has the potential to replace 18 F-FDG PET/CT due to its limited specificity in the head and neck cancer. Here, we present one case of papillary thyroid carcinoma, where 68 Ga-Trivehexin PET CT demonstrated accurate staging compared with 18 F-FDG PET/CT.

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