Ring-shaped nanoparticle assembly and cross-linking on lipid vesicle scaffolds.
basic_science · Level V
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- Record sourced from PubMed, PMID 39508507.
- Also identified by DOI 10.1039/d4sm01010h.
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Abstract
We show the assembly of carboxylate-modified polystyrene nanoparticles into flexible circular, ring-shaped structures with micrometer sized diameters around the base of surface-adhered lipid vesicles. The rings remain around the vesicles but disintegrate when the lipid membranes are dissolved in detergent. The aqueous medium allows carbodiimide-based cross-linking chemistry to be applied to the particle assemblies resulting in the preservation of the rings even after the lipid compartments are dissolved.