Trained immunity in the bone marrow: Hub of autoimmunity.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39515297.
- Also identified by DOI 10.1016/j.stem.2024.10.008.
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Abstract
An inappropriate induction of trained immunity in the bone marrow progenitors of immune cells has been described to underlie chronic inflammatory processes. Mills and colleagues' recently published paper in Cell Stem Cell shows that maladaptive trained immunity drives inflammation in autoimmune processes,<sup>1</sup> opening a new area of research in autoimmunity.
Medical subject headings
- Autoimmunity
- Bone Marrow