Respiratory Outcomes of Infants Born Extremely Preterm in the Necrotizing Enterocolitis Surgery Trial.

DeMauro, Sara B; Jensen, Erik A; McDonald, Scott A; Hintz, Susan; Tyson, Jon; Stevenson, David K; Blakely, Martin L; NICHD Neonatal Research Network · J Pediatr · 2025

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Abstract

The multicenter Necrotizing Enterocolitis Surgery Trial compared initial peritoneal drainage with laparotomy among infants with extremely low birth weight and surgical necrotizing enterocolitis or intestinal perforation. In this post hoc analysis of trial data, initial drainage was associated with adverse respiratory outcomes, both in hospital and through 2 years corrected age.

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