Cell-Free DNA in Hematologic Malignancies.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39531844.
- Also identified by DOI 10.1200/OP-24-00648.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Liquid biopsy techniques using cell-free DNA (cfDNA) play an increasingly important role in the characterization and surveillance of solid tumors. For blood cancers, molecular response assessment techniques using circulating malignant cells or bone marrow aspirates are well established in clinical care. However, cfDNA has an emerging role in hematology as well, with the opportunity for disease assessment and quantification independent of circulating disease burden or invasive biopsies. In this review, we discuss key technologies and clinical data for the utilization of cfDNA in lymphomas, myeloma, and leukemias.
Medical subject headings
- Hematologic Neoplasms
- Cell-Free Nucleic Acids