SnapShot: Targeted protein degradation.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39547212.
- Also identified by DOI 10.1016/j.cell.2024.10.025.
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Abstract
Targeted protein degradation strategies leverage endogenous cellular degradation machinery to selectively eliminate a protein of interest. Emerging technologies are opening avenues in drug discovery and functional characterization of intracellular, membrane, and extracellular proteins. To view this SnapShot, open or download the PDF.
Medical subject headings
- Proteolysis
- Proteins