Heart regeneration from the whole-organism perspective to single-cell resolution.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39548113.
- Also identified by DOI 10.1038/s41536-024-00378-8 and PMC identifier 11568173.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Cardiac regenerative potential in the animal kingdom displays striking divergence across ontogeny and phylogeny. Here we discuss several fundamental questions in heart regeneration and provide both a holistic view of heart regeneration in the organism as a whole, as well as a single-cell perspective on intercellular communication among diverse cardiac cell populations. We hope to provide valuable insights that advance our understanding of organ regeneration and future therapeutic strategies.