Advances in the Construction and Application of Bone-on-a-Chip Based on Microfluidic Technologies.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39555794.
- Also identified by DOI 10.1002/jbm.b.35502.
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Abstract
Bone-on-a-chip (BOC) models that based on microfluidic technology have widely applied to understand bone physiology and the pathogenesis of related diseases. In this review, we provide an overview of bone biology and related diseases, explain the advantages and applications of microfluidic technology in the construction of BOC models, and summarize their progress in physiology, pathology, and drug development. Finally, we discussed the problems to be solved and the future directions of microfluidic technology and BOC platforms, so as to provide a reference for researchers to design better BOC models.
Medical subject headings
- Lab-On-A-Chip Devices
- Bone and Bones