Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of Invasive Group A Streptococci Infection.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 39589137.
- Also identified by DOI 10.1093/cid/ciae524 and PMC identifier 11848273.
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Abstract
Antibiotic prophylaxis is often recommended for close contacts of index cases of invasive Streptococcus pyogenes infections. Using MarketScan data (2010-2019), we found no difference in infection rates between those who received and those who did not receive antibiotics but a 3-fold increased risk of adverse events in those who did receive antibiotics.
Medical subject headings
- Streptococcal Infections
- Streptococcus pyogenes
- Anti-Bacterial Agents
- Antibiotic Prophylaxis