Seasonal Patterns in Eosinophilic Esophagitis-Related Emergency Department Visits: A National Database Analysis.

Pan, Chun-Wei; Dominguez, Alejandro Nieto; Guifarro, Daniel; Danpanichkul, Pojsakorn; Pang, Maoyin · Am J Gastroenterol · 2025

cross_sectional · Level IV

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Abstract

This study investigates seasonal variations in eosinophilic esophagitis (EoE)-related emergency department visits among adults. We analyzed the National Emergency Department Sample (2016-2021), identifying adult patients with EoE using ICD-10 codes. Generalized additive models assessed seasonal patterns. Among 18,791 EoE-related emergency department visits, a significant seasonal variation was observed, peaking in summer and nadiring in winter. This pattern was consistent across all US regions. Seasonal dietary habits and social behaviors likely contribute to EoE exacerbations. Healthcare providers should emphasize management strategies during high-risk periods, particularly summer months and weekends.

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