Nonsteroidal anti-inflammatory drugs in the perioperative period: current controversies and concerns.
Level V
Where this comes from
- Record sourced from PubMed, PMID 39613528.
- Also identified by DOI 10.1016/j.bja.2024.10.018.
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Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase (COX)-2-specific inhibitors provide significant analgesic and opioid-sparing benefits. However, these analgesics are commonly avoided owing to concerns of potential adverse effects. The evidence for NSAID-related adverse effects is conflicting and of poor quality, and these analgesics are safer than what has been implied. Thus, it is imperative that NSAIDs or COX-2-specific inhibitors are administered routinely unless there are well-founded contraindications.
Medical subject headings
- Anti-Inflammatory Agents, Non-Steroidal
- Postoperative Pain
- Perioperative Care