PSMA Accumulation in Lower Extremity Lymphedema and Hydrocele.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 39629685.
- Also identified by DOI 10.1097/RLU.0000000000005613.
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Abstract
The development of radiolabeled small-molecule prostate-specific membrane antigen (PSMA) inhibitors has advanced molecular imaging in prostate cancer. The use of 177 Lu-PSMA is especially beneficial because its therapeutic β-emission combined with γ-radiation enables precise treatment and comprehensive imaging in patients with prostate cancer. We present a case of a prostate cancer patient who developed lower extremity lymphedema and hydrocele secondary to prior radiotherapy. Posttherapy whole-body imaging following 177 Lu-PSMA treatment revealed dermal backflow with a notable accumulation of soft tissue in the lower extremities and hydrocele.
Medical subject headings
- Antigens, Surface
- Glutamate Carboxypeptidase II
- Lymphedema
- Testicular Hydrocele