Mitochondrial respiratory supercomplexes gear up for heat generation in brown adipose tissue.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39631368.
- Also identified by DOI 10.1016/j.cmet.2024.10.022.
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Abstract
Mitochondrial energy conversion supplies cellular energy but can also provide heat in brown adipose tissue (BAT). In a recent study, Shin and Latorre-Muro et al.<sup>1</sup> show that respiratory supercomplexes in BAT are remodeled during cold to provide a tighter coupling, revealing a novel, physiologically important role for these supramolecular assemblies.
Medical subject headings
- Adipose Tissue, Brown
- Mitochondria
- Thermogenesis