Brain reboot: Enhancing neurogenesis and resilience.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39642859.
- Also identified by DOI 10.1016/j.stem.2024.11.004.
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Abstract
In this issue of Cell Stem Cell, Shen et al. investigate in vivo transient expression of Yamanaka factors (YFs) during embryogenesis and an adult mouse model of Alzheimer's disease (AD)-associated amyloidosis. These studies demonstrate that transient induction of YFs may be capable of enhancing neurogenesis and offer resilience against neurodegeneration.
Medical subject headings
- Neurogenesis
- Brain