MR-Guided PET Reconstruction: A Potential Advancement for Patients With Epilepsy.
case_report · Level V
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- Record sourced from PubMed, PMID 39652508.
- Also identified by DOI 10.1097/RLU.0000000000005631.
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Abstract
We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus. However, using MR-guided PET reconstruction, circumscribed hypometabolism was observed in the right-sided entorhinal cortex, compatible with the epileptogenic focus. The MR-guided PET reconstruction provided significantly improved gray/white matter differentiation, enhancing confidence in imaging interpretation.
Medical subject headings
- Positron-Emission Tomography
- Magnetic Resonance Imaging
- Epilepsy
- Image Processing, Computer-Assisted