Modern Treatment Delivery of Radiotherapy for Lymphomas and Leukemias: Making Every Gy Count.

Abstract

Radiotherapy has a long history in the treatment of lymphoma and leukemia, in which late toxicity outcomes have motivated current goals to improve how radiotherapy is delivered. Contemporary advanced radiotherapy techniques, including intensity modulated radiation therapy (IMRT), proton therapy, deep inspiration breath hold (DIBH), aim to reduce the risk of cardiac morbidity and second cancers caused by radiotherapy while maintaining local control. We use treatment of mediastinal and gastric lymphomas to introduce how modern techniques are chosen for optimal dose delivery, followed by an anatomic site-specific discussion of testicular, bone, and central nervous system disease.