Impact of Persistent Combat-Related PTSD on Heart Disease and Chronic Disease Comorbidity in Aging Vietnam Veterans.

Stellman, Steven D; Pless Kaiser, Anica; Smith, Brian N; Spiro, Avron; Stellman, Jeanne Mager · J Occup Environ Med · 2025

retrospective_cohort · Level III

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Abstract

To assess combat and combat-related posttraumatic stress disorder (PTSD) as risk factors for heart disease and noncardiac chronic disease comorbidity in deployed Vietnam veterans 50 years post-War. A random sample of 12,400 veterans was surveyed in 1984 & 1998, and a deployed subset (n=729) in 2000. Outcomes included probable PTSD and history of diagnosed chronic illnesses. Twenty-eight percent reported a diagnosed heart condition; combat exposure in Vietnam was a significant predictor (odds ratio = 1.92, 95% confidence interval = 1.13-3.31). Veterans with heart disease reported significantly more comorbid chronic illnesses, including arthritis and respiratory conditions: sleep apnea, emphysema, and asthma. Chronic illnesses were reported more often by men with PTSD. Emerging evidence suggests that 50 years after Vietnam combat and associated PTSD may contribute to heart disease and comorbid conditions.

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