Global collaboration between platform trials in surgery and anaesthesia.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39701591.
- Also identified by DOI 10.1093/bjs/znae262 and PMC identifier 11658830.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Large, randomized trials are the bedrock of evidence-based medicine, but the resources required to complete such trials greatly limit the number of important clinical questions that can be addressed within a reasonable period of time. Adaptive platform trials can identify effective, ineffective, or harmful treatments faster. These trials have been shown to deliver rapid evidence through the COVID-19 pandemic and are now being adopted across surgery and anaesthesia, with many opportunities for surgeons, anaesthetists, and other perioperative physicians to conduct and collaborate in platform trials.
Medical subject headings
- COVID-19