Potential nuances in renoprotective properties of estrogen in females.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 39746739.
- Also identified by DOI 10.1016/j.kint.2024.10.017 and PMC identifier 12063498.
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Abstract
A current study by Kitai et al. found that ovariectomy before estrogen/female sex hormone sensitization at puberty provided protection against kidney ischemia reperfusion injury, challenging the general consensus within the field that estrogen provides renoprotective function. These results are intriguing and could have important clinical implications, while requiring some clarification and substantiation of the conclusions reported.
Medical subject headings
- Reperfusion Injury
- Estrogens
- Ovariectomy
- Kidney