Cooperative integration of spatially resolved multi-omics data with COSMOS.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39747840.
- Also identified by DOI 10.1038/s41467-024-55204-y and PMC identifier 11696235.
- Licence recorded as CC BY-NC-ND.
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Abstract
Recent advancements in biological technologies have enabled the measurement of spatially resolved multi-omics data, yet computational algorithms for this purpose are scarce. Existing tools target either single omics or lack spatial integration. We generate a graph neural network algorithm named COSMOS to address this gap and demonstrated the superior performance of COSMOS in domain segmentation, visualization, and spatiotemporal map for spatially resolved multi-omics data integration tasks.