11C-Methionine PET/CT in Cryptococcus Meningoencephalitis.

Otomi, Yoichi; Teshima, Natsumi; Shinya, Takayoshi; Otsuka, Hideki; Harada, Masafumi · Clin Nucl Med · 2025

case_report · Level V

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Abstract

A 70-year-old man experienced an epileptic seizure. Subsequent MRI performed on close examination revealed high signal in the left occipital cortex on fluid-attenuated inversion recovery. Gadolinium contrast indicated enhancement along the cortex. 11C-Methionine PET/CT scan, performed to differentiate from a brain tumor, showed high uptake mainly along the left occipital lobe cortex. Spinal fluid examination revealed Cryptococcus neoformans, leading to a diagnosis of Cryptococcus meningoencephalitis.

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