The other side of the incretin story: GIPR signaling in energy homeostasis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39778517.
- Also identified by DOI 10.1016/j.cmet.2024.12.003.
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Abstract
Incretin receptor agonists have been effective in combatting obesity and diabetes. While the body of knowledge regarding the signaling mechanisms of glucagon-like peptide 1 (GLP-1) receptor agonists is ever-growing, glucose-dependent insulinotropic polypeptide receptor (GIPR) agonists are less understood. The previewed papers offer insight into the impact of adipose GIPR on energy and weight homeostasis.
Medical subject headings
- Receptors, Gastrointestinal Hormone
- Incretins
- Signal Transduction
- Homeostasis
- Energy Metabolism