Divide and conquer, mitochondrial edition: Subpopulations direct cellular energy and nutrient supply.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39778519.
- Also identified by DOI 10.1016/j.cmet.2024.12.006.
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Abstract
Mitochondria produce energy and building blocks essential for cell growth. How these competing processes are balanced and sustained during nutrient scarcity remains unclear. Ryu et al. uncover distinct mitochondrial subpopulations, one dedicated to ATP production and another to macromolecule synthesis, enabling cell growth and proliferation under nutrient-limiting conditions.
Medical subject headings
- Mitochondria
- Energy Metabolism
- Nutrients