Acral lentiginous melanoma. Part II. Staging, surgical management, the role of systemic therapy, shortcomings, and future directions.

Jaguan, Daniella; Thakker, Sach; Belzberg, Micah; Gulati, Nina; Campbell, Janeth R; DeClerck, Brittney K; Patel, Vishal A; In, Gino K · J Am Acad Dermatol · 2026

review · Level V

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Abstract

This comprehensive review navigates the clinical management and challenges of acral lentiginous melanoma, including staging, surgical interventions, and systemic therapies. Multimodality treatment and clinical trials are recommended for advanced cases.

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