Designer topological-single-atom catalysts with site-specific selectivity.

Chen, Weibin; Bao, Menghui; Meng, Fanqi; Ma, Bingbing; Feng, Long; Zhang, Xuan; Qiu, Zanlin; Gao, Song et al. · Nat Commun · 2025

basic_science · Level V

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Abstract

Designing catalysts with well-defined, identical sites that achieve site-specific selectivity, and activity remains a significant challenge. In this work, we introduce a design principle of topological-single-atom catalysts (T-SACs) guided by density functional theory (DFT) and Ab initio molecular dynamics (AIMD) calculations, where metal single atoms are arranged in asymmetric configurations that electronic shield topologically misorients d orbitals, minimizing unwanted interactions between reactants and the support surface. Mn<sub>1</sub>/CeO<sub>2</sub> catalysts, synthesized via a charge-transfer-driven approach, demonstrate superior catalytic activity and selectivity for NO<sub>x</sub> removal. A life-cycle assessment (LCA) reveals that Mn<sub>1</sub>/CeO<sub>2</sub> significantly reduces environmental impact compared to traditional V-W-Ti catalysts. Through in-situ spectroscopic characterizations combined with DFT calculations, we elucidate detailed reaction mechanisms. This study establishes T-SACs as a promising class of catalysts, offering a systematic framework to address catalytic challenges by defining site characteristics. The concept highlights their potential for advancing selective catalytic processes and promoting sustainable technologies.