Diffuse Large B-Cell Lymphoma With the "Leopard Man" Appearance on 18 F-FDG PET/CT.

Wang, Kangkang; Huang, Hao · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Subcutaneous nodules and masses as the primary manifestation of diffuse large B-cell lymphoma are exceedingly rare. We present 18 F-FDG PET/CT findings of multiple hypermetabolic nodules and masses distributed throughout the body, creating a characteristic "leopard man" appearance on the MIP image, in a 65-year-old man. An excisional biopsy of the right thigh mass confirmed the diagnosis of diffuse large B-cell lymphoma.

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