Case Report: 18 F-FDG PET/CT for FUO Due to Whipple Disease Infection.

Proto, Sara; Carrara Md, Lorenzo; Zanoni, Lucia; Attard, Luciano; Nanni, Cristina · Clin Nucl Med · 2025

case_report · Level V

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Abstract

We present the case of a 60-year-old man admitted to the hospital presenting with high FUO (fever of unknown origin), strong headache, face erythematous-desquamative cutaneous lesions, long history of abdominal pain, and diffuse myalgia. He was also previously treated with immunosuppressants and currently managed with corticosteroids for a seronegative rheumatic disease. Given the immunocompromised state, an infective etiology was suspected. The patient was referred, as part of standard clinical practice, to perform an 18 F-FDG PET/CT to identify potential causes of FUO.

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