A Randomized Control Trial Comparing the Effects of N-95 Respirator Versus Surgical Mask Use on Resting Metabolic and Respiratory Changes.

Abstract

This study aimed to compare physiological changes when wearing a N95 and surgical mask at rest. Forty-two subjects aged 18-55 (19 males; age 22.98 ± 3.83) were recruited. Respiratory and metabolic data were collected using indirect calorimetry under a hood. Volume of oxygen consumed, volume of CO 2 produced, and respiratory exchange ratio were measured. Respiratory rate, minute ventilation, and heart rate were recorded using Hexoskin Smart Shirt apparatus. Testing consisted of the following three 15-minute trials: no mask, surgical mask, and a N95 respirator. Rating of perceived exertion (RPE) was assessed. Results were analyzed using separate repeated measures analyses of variance. Respiratory exchange ratio, minute ventilation, and RPE were significantly higher in both conditions. Highest RPE reported while wearing the N95 mask. The use of a surgical or N95 face mask can cause small metabolic, respiratory, and RPE changes. Minor physiological changes were observed but remained within normally expected physiological parameters at rest.