Unlocking the potential of engineered immune cell therapy for solid tumors.

Albarrán-Fernández, Víctor; Angelats, Laura; Delgado, Julio; Gros, Alena; Urbano-Ispizua, Álvaro; Guedan, Sònia; Prat, Aleix · Nat Commun · 2025

basic_science · Level V

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Abstract

Adoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellular products with enhanced cytotoxicity, phenotype, and metabolism.