A reagent to access methyl sulfones.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39880857.
- Also identified by DOI 10.1038/s41467-024-55027-x and PMC identifier 11779965.
- Licence recorded as CC BY-NC-ND.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A chemical reagent to access methyl sulfones has been developed. Its reaction with various bis-nucleophiles leads to the rapid formation of previously unknown heteroaromatic methyl sulfones. Analogous strategy can also be used to construct alkyl-, CHF<sub>2</sub>-, CF<sub>3</sub>- and even bicyclo[1.1.1]pentane-containing derivatives. These compounds have been demonstrated to have a high potential for use in medicinal chemistry and coordination chemistry.