Ancient genomics and the origin, dispersal, and development of domestic sheep.

Daly, Kevin G; Mullin, Victoria E; Hare, Andrew J; Halpin, Áine; Mattiangeli, Valeria; Teasdale, Matthew D; Rossi, Conor; Geiger, Sheila et al. · Science · 2025

basic_science · Level V

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Abstract

The origins and prehistory of domestic sheep (<i>Ovis aries</i>) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled from across Eurasia. Genomes from Central Türkiye ~8000 BCE are genetically proximal to the domestic origins of sheep but do not fully explain the ancestry of later populations, suggesting a mosaic of wild ancestries. Genomic signatures indicate selection by ancient herders for pigmentation patterns, hornedness, and growth rate. Although the first European sheep flocks derive from Türkiye, in a notable parallel with ancient human genome discoveries, we detected a major influx of Western steppe-related ancestry in the Bronze Age.

Medical subject headings