Don't judge a book by its cover: Unusual presentations of pericardial disease.

Schiavone, William A; Majdalany, David S · Cleve Clin J Med · 2025

review · Level V

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Abstract

The presentation of pericardial disease can be unusual, and what is assumed to be pericardial disease may not be. Knowing pericardial and mediastinal anatomy is vital for understanding these unusual presentations. This review focuses on the history, physical examination, and fundamental diagnostic testing, integrated with pericardial and mediastinal anatomy and pathophysiology.

Medical subject headings