Challenges and hopes of gastrointestinal miRNA regulation: The example of stachyose.

Berthet, Louis; Viennois, Emilie · Cell Metab · 2025

basic_science · Level V

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Abstract

There is growing evidence that micro-RNAs (miRNAs) are key players in the regulation of gut health. In this issue of Cell Metabolism, Li et al.<sup>1</sup> uncovered that the dietary fiber stachyose can modulate the luminal miRNA load of the intestinal tracts by binding to HSP90β, thereby altering the gut's microbial composition.

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