Tumor "age" in early-onset colorectal cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39919707.
- Also identified by DOI 10.1016/j.cell.2024.12.003.
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Abstract
The incidence of early-onset colorectal cancer (EO-CRC) is surging, and by 2030, one-third of all CRCs will occur before the commonly recommended screening age of 50 years. The time required for EO-CRC to reach the metastatic stage is unknown, yet this knowledge is critical to tailor early-diagnosis screening strategies. Here, we discuss how defining a key biological feature of EO-CRC may be central to protecting young adults from an alarming and probably unprecedented tumor epidemic.
Medical subject headings
- Colorectal Neoplasms