Cognitive impairment in epilepsy progression: Adult neurogenesis loss at critical window.
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- Record sourced from PubMed, PMID 39919717.
- Also identified by DOI 10.1016/j.stem.2025.01.004.
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Abstract
The mechanisms underlying cognitive impairment in epilepsy remain poorly understood. Ammothumkandy et al.<sup>1</sup> reveal that the loss of adult immature neurons correlates with auditory verbal learning deficits in human mesial temporal lobe epilepsy during a critical disease period, underscoring the pivotal role of adult neurogenesis in specific cognitive domain.
Medical subject headings
- Neurogenesis
- Epilepsy
- Cognition Disorders
- Cognitive Dysfunction