Pre-birth stem cell education: A gift from mother's bugs.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 39919718.
- Also identified by DOI 10.1016/j.stem.2025.01.009.
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Abstract
The maternal gut microbiota undergoes significant changes during pregnancy and plays a pivotal role in offspring development. In this issue, Dang et al. demonstrate that modifying the maternal gut microbiome during pregnancy shapes offspring neural and intestinal stem cells via the mTOR pathway, with long-lasting effects on their functions.
Medical subject headings
- Stem Cells
- Gastrointestinal Microbiome