Mind the Gap: The Disconnect Between Clinical Trials and Real-World Oncology Patients.

Taha, Tarek; Hall, Emma; de Bono, Johann S · Eur Urol · 2025

review · Level V

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Abstract

The current model for oncology trials does not align with the realities of modern cancer care. More inclusive study designs could ensure that trial outcomes better reflect the diversity of cancer patients result in more effective, equitable, and patient-centered treatments. This shift is both an ethical imperative and a scientific necessity for advances in oncology.

Medical subject headings