Bio-inspired electronics: Soft, biohybrid, and "living" neural interfaces.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39984447.
- Also identified by DOI 10.1038/s41467-025-57016-0 and PMC identifier 11845577.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Neural interface technologies are increasingly evolving towards bio-inspired approaches to enhance integration and long-term functionality. Recent strategies merge soft materials with tissue engineering to realize biologically-active and/or cell-containing living layers at the tissue-device interface that enable seamless biointegration and novel cell-mediated therapeutic opportunities. This review maps the field of bio-inspired electronics and discusses key recent developments in tissue-like and regenerative bioelectronics, from soft biomaterials and surface-functionalized bioactive coatings to cell-containing 'biohybrid' and 'all-living' interfaces. We define and contextualize key terminology in this emerging field and highlight how biological and living components can bridge the gap to clinical translation.
Medical subject headings
- Tissue Engineering
- Electronics
- Biomimetics